

IPO Profile: China Online Education Group (51Talk)
Company Details
Shanghai
86-105-692-8909
Description: Beijing Dasheng Zhixing Technology Co Ltd is a China-based company principally engaged in the provision of online education training. The Company operates its business through operation of its own brand 51Talk, which provides online English courses including one-to-one talk with foreign teachers and others.
IPO Details
Exchange and Ticker: NYSE: COE
Filing Range: Â 2.4 million shares at $18 to $20
Offering Price: $19
Price as of 6/10/16: $18.98
Offering Size: $46 million
Shares Outstanding: 19.6 million
Market Capitalization on 6/30/16: $389 million
Price as of 6/30/16: $19.83
Investment Details
Backers
- DCM Ventures
- Sequoia Capital
- Shunwei Capital Partners
- Zhen Fund
- Xianfeng Huaxing Venture Capital Ltd
- Shunwei Capital Partners
Financing Rounds
Date     Amount ($M)   Valuation ($M)
6/28/13Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â $3MÂ Â Â Â Â Â n/a
12/19/13Â Â Â Â Â Â Â Â Â Â Â Â Â $12MÂ Â Â Â n/a
10/24/14Â Â Â Â Â Â Â Â Â Â Â Â Â $55MÂ Â Â Â n/a
8/31/15Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â $20MÂ Â Â Â n/a
IPO Profile: Clearside Biomedical Inc
Company Details
Alpharetta, Ga.
678-270-3631
Description: Clearside Biomedical Inc is a late-stage clinical biopharmaceutical company. The company is developing drug therapies to treat blinding diseases of the eye. The Company’s product candidates are focused on diseases affecting the retina and choroid, especially diseases associated with macular edema, and are injected into the suprachoroidal space (SCS) adjacent to the choroid, using its SCS Microinjector. With the SCS injection, its product candidates are directly administered to the retina and choroid. Its product candidates are CLS-1001, CLS-1003 and CLS-1002. CLS-1001 and CLS-1003 are based on commonly used ophthalmic drugs. Its CLS-1001 program is being developed for the treatment of macular edema associated with non-infectious uveitis. CLS-1001 consists of an SCS injection of Zuprata, its preservative-free formulation of the corticosteroid triamcinolone acetonide (TA), specifically designed to be administered through its SCS Microinjector.
IPO Details
Exchange and Ticker: Nasdaq: CLSD
Filing Range: 4 million shares @ $14 to $16
Offering Price: $7
Close price as of 6/2/16: $7.25
Offering Size: $50.4 million
Shares Outstanding: 19.6 million
Underwriters: Cowen, Stifel Nicolaus & Co Inc
Co-manager: Wedbush Securities, Needham & Co LLC
Company Counsel: Cooley LLP
Manager Counsel: Latham & Watkins
Auditor: Ernst & Young LLP
Market Capitalization on 6/30/16: $137.3 million
Price as of 6/30/16: $7.01
Investment Details
Backers
- Hatteras Venture Partners
- GRA Venture Fund LLC
- Mountain Group Capital LLC
- Rock Springs Capital Management LP
- Aju IB Investment Co Ltd
- RosnanoMedInvest OOO
- UNC Kenan-Flagler Private Equity Fund
Financing Rounds
Date     Amount ($M)   Valuation ($M)
1/5/12Â Â $4MÂ Â Â Â Â Â n/a
1/31/13Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â $7.3MÂ Â n/a
9/15/14Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â $15.6M n/a
12/8/15Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â $14.5M n/a
Source: Thomson Reuters data.
IPO Profile: Nanthealth Inc
Company Details
Culver City, Calif.
855-839-8157
Description: NantHealth Inc, formerly Nant Health, LLC, is an evidence-based, personalized healthcare company. The company’s systems-based approach to personalized healthcare applies diagnostics tailored to specific molecular profiles of patient tissues and integrates this molecular data in a clinical setting with real-time biometric signal and phenotypic data to track patient outcomes and deliver medicine. It has developed an integrated and adaptive Systems Infrastructure, Knowledge Platform, Provider Platform and Payor Platform known as Comprehensive Learning Integrated NantHealth Intelligent Clinical System, which includes its software, middleware and hardware systems infrastructure that collects, indexes, analyzes and interprets molecular, operational and financial data points derived from various sources. Its Systems Infrastructure includes software, middleware and hardware modules, NantOS, which organize and integrate data streams that form foundation of its adaptive learning system.
IPO Details
Exchange and Ticker: Nasdaq: NH
Filing Range: 6 million shares @ $12:50 to $15:50
Offering Price: $14
Price as of 6/2/16: $18.59
Offering Size: $91 million
Shares Outstanding: 120.7 million
Underwriters: Jefferies LLC, Cowen
Co-manager: FBR Capital Markets Corp, First Analysis Securities, Canaccord Genuity
Company Counsel: Wilson Sonsini Goodrich & Rosati
Manager Counsel: Cooley LLP
Auditor: Ernst & Young LLP
Market Capitalization on 6/30/16: $1509.2 million
Price as of 6/30/16: $12.50
Investment Details
Backers
- Celgene Corp
- Verizon Ventures
Financing Rounds
Date     Amount ($M)   Valuation ($M)
10/24/12             n/a        n/a
5/13/14Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â $135MÂ n/a
10/1/14Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â $320MÂ n/a
1/12/16Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â $52.5M n/a
Source: Thomson Reuters data.
IPO Profile: Selecta Biosciences Inc
Company Details
Watertown, Mass.
617-923-1400
Description: Selecta Biosciences Inc is a United States-based clinical-stage biopharmaceutical company. The company is engaged in developing targeted therapies that use immunomodulators encapsulated in nanoparticles to induce antigen-specific immune responses to prevent and treat disease. Its Synthetic Vaccine Particles (SVP) technology is a platform, which is capable of incorporating a range of antigens and immunomodulators for the development of SVP products for either inducing antigen-specific tolerance or activating the immune system. Its pipeline includes programs for various indications, including gene therapy, food allergy and malaria. Its pipeline includes SEL-212, which is a therapeutic enzyme indicated for refractory gout; SEL-070, which is indicated for smoking cessation and relapse prevention, and SEL-701, which is indicated for the treatment of human papillomavirus (HPV)-associated cancer. SEL-212 consists of SVP-Rapamycin co-administered with pegsiticase, its pegylated uricase.
IPO Details
Exchange and Ticker: Nasdaq: SELB
Filing Range: 4.25 million shares @ $14 to $16
Offering Price: $14
Close price as of 6/22/16: $14
Offering Size: $70 million
Shares Outstanding: 17.9 million
Underwriters: UBS Securities Inc, Stifel Nicolaus & Co Inc, Canaccord Genuity, Needham & Co LLC
Company Counsel: Latham & Watkins
Manager Counsel: Cooley LLP
Auditor: Ernst & Young LLP
Market Capitalization on 6/30/16: $250.4 million
Price as of 6/30/16: $13.99
Investment Details
Backers
- Polaris Venture Partners
- Flagship Ventures
- OrbiMed Advisors LLC
- NanoDimension Management Ltd
- Rossiiskaia Korporatsiia Nanotekhnologii GK
- Sanofi-Genzyme BioVentures
- Osage Partners
- Aju IB Investment Co Ltd
- Eminent Venture Capital Corp
- I2Bf Global Ventures
Financing Rounds
Date     Amount ($M)   Valuation ($M)
- 5/2/08 $2.5MÂ Â n/a
- 12/19/08 $15.1M n/a
- 3/22/10 $15MÂ Â Â Â n/a
- 10/27/11 $23.8M n/a
- 4/9/14 $5.3MÂ Â n/a
- 8/28/14 $10.4M n/a
- 10/15/14 $9.5MÂ Â n/a
- 9/3/15 $38MÂ Â Â Â n/a
Source: Thomson Reuters data.
IPO Profile: Syros Pharmaceuticals Inc
Company Details
Watertown, Mass.
617-744-1340
Description: Syros Pharmaceuticals Inc is a United States-based biopharmaceutical company. The company focuses on discovering and developing medicines that control the expression of genes with the aim of treating cancer and other serious diseases. It has a gene control platform that provides the company with lens to identify genes that become dysregulated in diseased cells. Its platform maps gene control circuits in human disease tissue and identifies optimal points of intervention for therapeutics. Its platform identifies genes controlling cell state and disease. Through the construction of gene control maps, molecular targets can be identified in the way that disease driving genes, such as oncogenes has been identified through mutational analysis. Its platform can identify specific patients that respond to these gene control therapies. It is advancing several preclinical programs towards the clinic for the treatment of cancer.
IPO Details
Exchange and Ticker: Nasdaq: SYRS
Filing Range: 4.30 million shares @ $14 to $16
Offering Price: $12.50
Close price as of 6/30/16: $18.15
Offering Size: $50 million
Shares Outstanding: 22.8 million
Underwriters: Cowen, Piper Jaffray Cos
Co-manager: Wedbush Securities
Company Counsel: Wilmer Cutler & Pickering
Manager Counsel: Cooley LLP
Auditor: Ernst & Young LLP
Market Capitalization on 6/30/16: $413.1 million
Price as of 6/30/16: $18.15
Investment Details
Backers
- Polaris Venture Partners
- Flagship Ventures
- Aisling Capital LLC
- Arch Venture Partners LLC
- Alexandria Venture Investments
- Wuxi Healthcare Ventures
- Casdin Capital LLC
- Deerfield Management Company LP
Financing Rounds
Date     Amount ($M)   Valuation ($M)
8/15/12               n/a        n/a
4/11/13               n/a        n/a
10/24/14             n/a        n/a
1/12/16               n/a        n/a
Source: Thomson Reuters data.
IPO Profile: Twilio Inc
Company Details
San Francisco, Calif.
415-236-0997
Description: Twilio Inc offers cloud communications platforms. The company enables developers to build, scale and operate real-time communications within software applications. It Programmable Communications Cloud software enables developers to embed voice, messaging, video and authentication capabilities into their applications via its Application Programming Interfaces. The Super Network is its software layer that allows its customers’ software to communicate with connected devices globally. It interconnects with communications networks around the world and continually analyzes data to optimize the quality and cost of communications that flow through its platform. The Programmable Communications Cloud consists of software products that can be used individually or in combination to build rich contextual communications within applications. The Programmable Communications Cloud includes Programmable Voice; Programmable Messaging; Programmable Video; Use Case APIs, and Add-on Marketplace.
IPO Details
Exchange and Ticker: NYSE: TWLO
Filing Range: 10 million shares @ $12 to $14
Offering Price: $15
Price as of 6/23/16: $28.79
Offering Size: $150 million
Shares Outstanding: 82.2 million
Underwriters: Goldman Sachs & Co, JP Morgan Securities Inc, Allen & Co Inc, Canaccord Genuity, JMP Securities LLC, William Blair & Co, Pacific Crest Securities Inc
Company Counsel: Goodwin Procter LLP
Manager Counsel: Latham & Watkins
Auditor: KPMG LLP
Market Capitalization as of 6/30/16: $3 billion
Price as of 6/30/16: $36.50
Investment Details
Backers
- Bessemer Venture Partners
- Redpoint Ventures
- Rowe Price Threshold Partnerships
- Fidelity Investment Funds II
- Salesforce Ventures
- Altimeter Capital Management LP
- Union Square Ventures LLC
- DFJ
- 500 Startups
- The Founders Fund
Financing Rounds
Date     Amount ($M)   Valuation ($M)
- 3/2/09 n/a        n/a
- 12/30/09 $3.7MÂ Â n/a
- 11/2/10 $12MÂ Â Â Â n/a
- 8/31/11 n/a        n/a
- 12/7/11 $17MÂ Â Â Â n/a
- 5/31/12 n/a        n/a
- 5/16/13 $70MÂ Â Â Â n/a
- 3/2/15 $6.3MÂ Â n/a
- 4/24/15 $100MÂ n/a
- 7/29/15 $130MÂ n/a
Source: Thomson Reuters data.
Photo of Jeff Lawson, (center) founder, cheif executive and chairman of Twilio, takes a selfie photo during his company’s IPO on the floor of the NYSE in New York City, June 23, 2016 courtesy of Reuters/Brendan McDermid